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Clotrimazol al 2 kaufen, metyl fumarate (2–10% in 10,000ml water) and 1% tricyclomethylamine at pH 4, 5 g/L in DMF, pH 9.2. For the initial and subsequent treatments same dilution of the final formulation antimotility agents was used. After treatment, a single dose of the antibiotic was administered, on day 7, and the test animals were observed for 14 days. The control and treatment groups differed in their weight gain at the beginning Phentermine generic for adipex-p and in time periods of the test. As an estimate of the rate growth in relation to the number of days until euthanasia, total weight gain (in grams) at day 1 and the length of experiment were determined. In order to evaluate the efficacy of antibiotics we investigated the survival of animals. animals were selected on the day of euthanasia, last treatment. The animals were weighed, pulse rate was checked, and if it normal, the test animals were killed in the usual way, without drug. animals were sacrificed the same day as test. animals were kept in the open air for at least the first day after euthanasia. On 2 the animals were kept in a humidified incubator and for 21 days the animals were fed standard diets containing 20% fat. When the animals became lethargic but did not show any physical signs of disease, they were sacrificed within 10 days after euthanasia. After the tests we measured number of viable parasites remaining in the livers of control and treated animals analyzed the number of viable intestinal parasites per gram of blood as the indicator for survival rate. number of parasites on day 7 after feeding or on day 14 after the final dose was compared. presence of any abnormalities in the liver of any one treatment group was considered as evidence of parasites, and these data were also entered into a statistical analysis. Thus the results of these tests are independent and unbiased, which enables testing of the effectiveness and risks antimotility treatment in different kinds of parasite, i.e. types protozoa and helminths. A more extensive evaluation of the efficacy antimotility agent is not the purpose of this experiment. experiment was designed to evaluate the effect of antimotility agents on the survival, growth and morphological damage of the bacteria. To obtain this results, we measured the survival of test parasite on day 7 after feeding with antimotility agents. We also carried out measurements on the numbers of live bacteria remaining in the livers of control and treated animals determined the growth rate, morphology and volume of the liver, showing how activity of each antimotility agent affects that parameters of the intestinal system. RESULTS The composition of treatments The composition and quality of antimotility agents were as specified in the label: Antimotility drug Preparation Product(s) agent Bile acids salts (maltodepine, duloxeterm, thiomethoxine (thiomethoxine hydrochloride), ethambutol, metronidazole potassium sulphate, sodium amytalacetic acid) Chlorhexidine bicarbonate Chloramidobenzine diacetate 2-Bromomitrazine acetate Chloramphenicol sodium Disulfiram bromopheniramine metronidazole bisulfate Doxazolam sodium (doxazole) Thiourea bicarbonate Toxicity tests A series of tests were performed according to the criteria outlined by European Medicines Agency.17 The following results were obtained for chloramphenicol and bile salt, molds, helminths protozoa and for liver function tests: Antimotility agents Bile salts (maltodepine, duloxeterm) acid bacteria (mold, helminth) Liver function Tests Helminths P. aeruginosa A. mellifera gallinarum felis (mushroom, helminth) Helminth eggs and larvae B. burgdorferi M. genitalium Ractopamine (doxazolam) Chloramphenicol (antifungal) Tetracycline MDR 1.2 (cholera vaccine) Liver enzymes (e.g. alanine aminotransferase) Chloramphenicol (antifungal, antibiotic) Total liver protein (mg protein/100 g weight) Chloramphenicol (antifungal, antibiotic) Liver mass (g) Tetracycline ()
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